A continuing review shall be performed once a year by the IRB for every ongoing human subject research project.  A continuing review for a project eligible for expedited review shall be conducted by expedited review, in the same fashion as the initial review.  A continuing review for other projects shall be conducted in the same fashion as the initial other review.

The IRB shall determine if any human subject research project that will continue for more than one year requires a continuing review more often than annually.  Such a project shall be scheduled for more frequent reviews in accordance with a schedule that the IRB determines to be appropriate for that particular project.  In the course of each continuing review, the IRB shall consider whether the project requires verification from sources other than the researcher that no material changes have occurred since prior IRB review.

Projects approved as "exempt from further review" do not need to be reviewed on an annual basis unless changes have been made to the original protocol.